About your role
You will work with a large team of clinicians and translational researchers setting up a workflow for the biobanking of materials collected from a cohort of individuals undergoing a lifestyle intervention. In addition to this general task, there will be three subprojects that will be your main responsibility. When writing your motivation letter, indicate which subproject you have a preference for and why:
- Subproject 1 (led by Dr. Juan J. García Vallejo): You will collaborate with a team of experts in setting up comprehensive multi-layered immune monitoring strategies spanning over 70-marker panels and time-lapse flow cytometry. You will work together with a postdoc on creating novel data models and identifying interesting biomarker leads for the development of next-generation miniaturized assays for screening purposes.
- Subproject 2 (led by Dr. Rubina Baglio): Within our group, you will investigate how lifestyle and biological diversity influence immune-metabolic status and contribute to the development of metabolic diseases. You will develop and apply a cutting-edge, highly multiplexed immune-metabolic profiling methodology and functional assays to unravel these complex interactions. In addition, you will explore how circulating factors, including extracellular vesicles, reprogram immune cell metabolism and function, with the goal of identifying strategies to counteract their detrimental effects and inform future therapeutic interventions.
- Subproject 3 (led by Dr. Jan van den Bossche): Within IMMUNOMETLAB, you will perform pioneering immunometabolism research to advance our understanding on how changes in metabolic activity translate into altered immune functions and set the balance between health and disease. You will develop new assays, including time-lapse cytometry combined with single-cell metabolic and functional readouts, to determine the interplay between immune cell profiles to metabolic activity and disease.
About you- a Master’s degree (or equivalent) in biomedical sciences, molecular biology, medicine or a related field (applicants in the final stage of their degree are welcome to apply);
- a strong background in immunological and/or immune-metabolic research with a translational aim;
- experience with (spectral) flow cytometry, and strong interest in high-dimensional data analysis and biostatistics;
- you can work independently and thrive in a multidisciplinary academic environment;
- you communicate fluently in English, both verbally and in writing.
Our offer- A flying start to your career in scientific research.
- Plenty of room for your drive to shape tomorrow's healthcare.
- Working on large-scale and in-house research, with motivated colleagues from all over the world.
- You will be employed by Amsterdam UMC Research BV.
- A contract for 12 months, with the intention to extend for a total of 4 years. The Guideline PhD contract applies to this vacancy.
- Salary scale OIO: € 3.108 to € 3.939 gross based on full-time employment (depending on education and experience) and a year-end bonus of 8.3%. Calculate your net salary here.
- Holiday hours: 190.4 per year for fulltime and a possibility to save additional hours.
- Pension accrual with BeFrank, a modern, comprehensible and fairly priced pension.
- For >7 km each way, 100% reimbursement for public transport travel costs and, for private transport, €0.18 per km up to a maximum of 40 km each way.
- Do you prefer walking or cycling? Take advantage of our good bike scheme. Moreover, you will receive a reimbursement of €0.18 per km.
Watch this video with more information about joining Amsterdam UMC Research BV.
