About your role
It is now well established that metabolic configuration is a key regulator of immune cell function and therefore an important factor in the development of improved diagnostics and therapies. Although opportunities to profile immunometabolism have expanded rapidly in recent years, these approaches are still not routinely applied in most academic and industrial laboratories. To advance the field, accessible and standardized tools are needed to lower the barrier to immunometabolism research and support the translation of fundamental discoveries into clinical applications.
Aim of the positionApply immunometabolic profiling across immune cell types and disease contexts.
Objectives
- Establish and standardize cytometry-based immunometabolic profiling panels to enable comprehensive analysis of key metabolic pathways across species.
- Identify metabolic and lipid metabolic profiles in health and disease, and determine conserved or disease-specific signatures across cells, tissues and disease states (e.g. multiple sclerosis, lung cancer, cardiovascular disease).
- Investigate how selected interventions reshape immune cell metabolism, including lifestyle-related changes (such as diet), immunometabolic modulators and commonly used clinical drugs, to inform diagnostic biomarkers and targeted immune interventions.
About youWe are looking for a highly motivated researcher with the following qualifications and experience:
- a completed master’s degree in biomedical sciences, immunology, medicine, bioinformatics or a related field;
- strong interest in immunometabolism, immune cell biology and translational research;
- affinity with experimental and/or data-driven research, such as flow cytometry, multi-omics, single-cell technologies or lipidomics (experience is a plus, motivation to learn is essential);
- analytical, structured and curious, with attention to reproducibility and standardization;
- strong communication skills and motivation to work in an interdisciplinary and international research environment.
Note: Important strict eligibility criteria according to MARIE SKLODOWSKA CURIE programs:
You
must be in the first four years of your research career and not yet have been awarded a doctoral degree at the time of recruitment.At the time of the application deadline, you
must also have a Master's degree and
must not have resided or carried out your main activity (work, studies, etc.) in the Netherlands for more than 12 months in the three years prior to the contract start date.A 3-6 month internship in another institution/country will be part of the Marie Curie project.
Our offer- A contract for 12 months, with the intention to extend for a total of 4 years. The Guideline PhD contract applies to this vacancy.
- Salary scale OIO: € 3.108 to € 3.939 gross based on full-time employment (depending on education and experience) and a year-end bonus of 8.3%. Calculate your net salary here.
- Vacation hours: 190.4 per year based on full-time employment and possibility to save additional hours.
- Free and unlimited access to our online learning environment GoodHabitz.
- Pension accrual with the ABP, of which we pay 70% of the premium.
- Reimbursement of your public transport expenses. Do you prefer biking to work? Then we have a good bicycle scheme.
- An active staff association and Jong Amsterdam UMC association, both of which organize fun (sports) activities and events.
