About your role
As a researcher within this project, your main goal is to translate complex AI challenges into clinically meaningful tools that improve cancer treatment monitoring. You will contribute to the development of the Composite Response Index (CRI), a novel biomarker that integrates traditional tumor volume changes with a Margin Clarity Score (MCS) derived from AI-based uncertainty models.
Your key responsibilities include:
- Correlating clinical ambiguity in tumor delineations with patient treatment responses using radiotherapy and surgical datasets.
- Benchmarking different AI uncertainty methods to determine the most effective approach for capturing clinical disagreement.
- Developing and validating the CRI biomarker using large-scale clinical trial cohorts.
- Building interpretable predictive models using Explainable AI (XAI) to support clinical decision-making.
- Collaborating closely with clinical end-users in dedicated sessions to refine the framework and ensure it fits multidisciplinary team workflows.
About youWe are looking for a candidate with a strong technical background who is motivated to apply AI to clinically relevant challenges in oncology. The position offers substantial room for initiative in shaping the research direction and methodological approach.
Key requirements and attributes:
- A PhD in Artificial Intelligence, Medical Image Analysis.
- Experience with deep learning and a strong interest in (or experience with) model uncertainty estimation.
- Ability to work effectively across disciplines and communicate complex AI concepts to clinicians such as surgeons and radiologists.
- Strong analytical skills and experience handling complex imaging datasets from multi-institutional cohorts.
- A translational mindset, with motivation to develop tools such as open-source code, analytical frameworks or clinical reporting add-ons that can directly impact patient care and surgical decision-making.
Our offer- A flying start to your career in scientific research.
- Plenty of room for your drive to shape tomorrow's healthcare.
- Working on large-scale and in-house research, with motivated colleagues from all over the world.
- You will be employed by Amsterdam UMC Research BV.
- A contract for 12 months, with the intention to extend for a total of 2 years.
- Salary scale 10: € 3.598 to € 5.669 gross or salary scale 11: € 4.818 to € 6.594 gross based on full-time employment (depending on education and experience) and a year-end bonus of 8.3%. Calculate your net salary here. As of 1 July 2026, the salary will be increased by 3.5% in accordance with the collective labor agreement (CAO UMC).
- Holiday hours: 190.4 per year for fulltime and a possibility to save additional hours.
- Pension accrual with BeFrank, a modern, comprehensible and fairly priced pension.
- For >7 km each way, 100% reimbursement for public transport travel costs and, for private transport, €0.18 per km up to a maximum of 40 km each way.
- Do you prefer walking or cycling? Take advantage of our good bike scheme. Moreover, you will receive a reimbursement of €0.18 per km.
Watch this video with more information about joining Amsterdam UMC Research BV.
