1-2 Postdoctoral positions in Computational Biochemistry

Uppsala University, Department of Cell and Molecular Biology

Are you interested in working with computer simulations of enzymes, with the support of competent and friendly colleagues in an international environment? Are you looking for an employer that invests in sustainable employeeship and offers safe, favourable working conditions? We welcome you to apply for a postdoctoral position at Uppsala University. 

The Department of Cell and Molecular Biology is organized into seven research programs which all focus on different areas of cell and molecular biology: Computational Biology and Bioinformatics, Microbiology and Immunology, Molecular Biology, Molecular Biophysics, Molecular Evolution, Molecular Systems Biology and Structural Biology. The scientific basis of what we do lies in biology, but our research overlaps with other areas such as medicine, computer science, mathematics, chemistry, engineering sciences and physics. In total, we are over 200 staff and ~60 Ph.D. students. Please read more about the department’s work at https://icm.uu.se. The positions are available in Johan Åqvist’s research group at the program of computational biology and bioinformatics. The research is focused on computer simulations of enzyme reactions, with particular focus on enzyme evolution and adaptation, in collaboration with experimental groups.

Duties
The research project involves computational analysis of enzyme evolution and adaptation to extreme environments. The work will involve molecular dynamics, EVB and QM/MM computer simulations, free energy calculations, molecular docking, bioinformatics analysis and modelling of protein structure, as well as software development.

Requirements
PhD degree in computational chemistry, structural biology, biophysics or a foreign degree equivalent to a PhD degree in either of these areas. The degree needs to be obtained by the time of the decision of employment. Those who have obtained a PhD degree three years prior to the application deadline are primarily considered for the employment. The starting point of the three-year frame period is the application deadline. Due to special circumstances, the degree may have been obtained earlier. The three-year period can be extended due to circumstances such as sick leave, parental leave, duties in labour unions, etc. 

Documented experience of computational chemistry and structural biology is required, as well as scientific skills demonstrated through publications and presentations at national and international conferences. The project involves collaboration between different disciplines and interpersonal skills are therefore essential. In ranking qualified applicants, personal skills such as ability to communicate, collaborate and work independently, as well as scientific maturity and creativity, will be considered particularly important. Excellent oral and written communication skills in English are an absolute requirement as the working environment is international.

Additional qualifications
Experience from molecular dynamics simulations, modelling of enzyme reactions, structural bioinformatics and experimental biochemistry will be considered as particularly meritorious skills.

About the employment
The employment is a temporary position of at least two and at most three years according to central collective agreement. Full time position. Starting date 2024-11-01 or as agreed. Placement: Uppsala.

For further information about the position, please contact: Johan Åqvist +4618 471 41 09, Johan.Aqvist@icm.uu.se.

Please submit your application by 1st of October 2024, UFV-PA 2024/2877. 

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Uppsala University is a broad research university with a strong international position. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all of our 7,600 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of Sweden’s most exciting workplaces.

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