The project entails developing a novel biointerface for vascular stents that promote tissue integration via cell proliferation and modulated cell adhesion without the induction of abberant tissue responses such as fibrosis. Together with the department of surgery, focusing on vascular surgery, we aim to to ulitse high-throughput biomaterial screening to identify the optimal physicochemical surface properties to enhance vascular tissue stimulation. The findings will be translated to an actual Endovascular Aneurysm Repair (EVAR) device and tested in vivo. The project has a high clinical translational character where pre-clinical, clinical and industrial partners closely work together.
The position requires knowledge across disciplines of chemistry, cell biology, and physicochemical analysis and surface characterization and should have a PhD degree in related areas. Focus will be on physical chemistry of interfaces and tissue integration with a strong engineering and clinical translational character. Knowledge and experience with surface chemistry and characterization, cell biology, and imaging approaches such as SEM, and Fluorescence Microscopy (Laser Scanning Confocal Microscopy) is required. It is desired to have cell biological expertise both theoretical and practical with preferably affinity to the blood-brain-barrier. The person we seek is highly motivated and able to work in between departments of various expertise and has affinity to clinical translation and working with companies. Excellent writing and communication skills are required as well as reporting skills for preparation of progress reports for the partners and funding agency.
