Snabbfakta
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- Oxford
Ansök senast: 2024-12-31
Postdoctoral Research Associate in Chemical Biology and Bioengineering
Department of Chemistry, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA We are looking to recruit a Postdoctoral Research Associate in Chemical Biology and Bioengineering to join the Aye laboratory based at the Oxford Department of Chemistry. The Aye laboratory is a multidisciplinary laboratory focusing on reactive small-molecule metabolite signaling as it pertains to intra- and intercellular communication and drug discovery. We have pioneered numerous novel and multi-award-winning chemical biology concepts and techniques that have been applied to important biological questions. This project and the role will build on previously-published foundational studies, and encompass wide-ranging areas in the broader context of organic chemistry and chemical biology including small-molecule probe engineering: including, (1) projects aimed at understanding and reprogramming subcellular metabolite trafficking and signaling mechanisms through the design and application of novel small-molecule probes; (2) projects targeting chemistry-driven innovations of advanced spatial & functional omics methods in multiple living models for fundamental and disease-specific investigations; (3) development of selective small-molecule inhibitors targeting proteins/pathways essential in anticancer and immunotherapeutic development. There is possibility to learn cell-based assays and cutting-edge biochemical assays, in line with candidates’ interest to diversify and successful and timely production of desired molecules (and subsequent SAR). The successful candidate will hold a Ph.D., or be close to completion, in chemistry or biological or medicinal chemistry, or broader life sciences. We welcome all interested aspiring interdisciplinary researchers with diverse backgrounds. Experience in organic chemistry, bioengineering, or biotechnology is a plus, but not strictly required. We offer a laboratory that has won numerous awards lying at a nexus between numerous fields interfacing with chemistry. The successful candidate will enjoy unique state-of-the-art instrumentation, a team-playing environment where they can learn and develop, and projects that are aiming to make real-world impact. The facilities and infrastructure at Oxford are also fantastic. More information about our research group, including other active research themes, can be found at This position is available immediately.
