Research Assistant – Protein Expression (12-Month FTC)
Job Title: Research Assistant – Protein Expression (12-Month Fixed-Term Contract)
Location: London, UK on-site full time
About the Company:
A leading biotechnology company dedicated to transforming cancer treatment. With a strong pipeline of complex biologics and a commitment to advancing oncology research, the company fosters a collaborative and dynamic environment for scientific discovery.
Role Overview:
An exciting 12 month FTC opportunity is available for a Research Associate in Protein Expression to support the in-house protein expression platform. The role involves the design, production, and optimization of recombinant proteins and antibodies, contributing to early-stage drug discovery and preclinical development.
Key Responsibilities:
- Design and construct plasmids for recombinant protein expression in suspension CHO/HEK cells, including antibodies, alternative formats, and antigens.
- Perform DNA amplification and purification from bacterial cells at various scales.
- Conduct transient expression of antibodies, ranging from milligram to gram scale.
- Produce antibodies from stable cell lines using fed-batch processes in mid-scale bioreactors.
- Explore and implement new technologies in protein expression.
- Maintain detailed records of experimental results and register expression batches.
- Collaborate with cross-functional teams.
Essential Qualifications & Experience:
- Industry experience in DNA purification at mini to giga scales.
- Proficiency in transiently expressing antibodies in CHO and/or HEK293 cells.
- Experience in optimizing expression titre and quality of antibodies and recombinant proteins.
- Familiarity with biomolecule tracking software such as Genedata Biologics.
Why Join?
- Be part of a pioneering team.
- Gain exposure to cutting-edge biotechnology in a supportive and dynamic environment.
- Work in a company committed to professional growth and inclusivity.
If you are a motivated and enthusiastic team player with a passion for protein expression and oncology research, we encourage you to apply.
