Research Assistant - Strand, London, WC2R 2LS

Research Assistant - Strand, London, WC2R 2LS

About us

The Translational Immune Effector Cell Therapy Group at the Rayne Institute, Denmark Hill campus, translates novel chimeric antigen receptor T (CAR T) cells into the clinic for the treatment of patients with blood cancers.

About the role

We are seeking an experienced Research Assistant to join the Translational Immune Effector Cell Therapy Group at the Rayne Institute, Denmark Hill campus.  We are a new group which translates novel chimeric antigen receptor T (CAR T) cells into the clinic for the treatment of patients with blood cancers.

We perform pre-clinical work to aid submission to regulatory authorities. We develop molecular and flow cytometry assays to detect CAR T cells in patient samples for translational studies. Our laboratory is closely linked with the clinical haematology department at King’s College Hospital which has one of the largest CAR-T cell programmes in the UK. Diseases that we are currently targeting include multiple myeloma and B cell lymphoma, for which we have funding from Blood Cancer UK and Cancer Research UK.

Candidates applying for this role should have significant experience working within immunology and should be competent in flow cyometry including assay optimisation and panel design, previous experience using spectral flow cytometry would be ideal. Additionally, experience with PCR, and ideally digital droplet PCR is desirable.  Previous experience manufacturing research grade CAR T cells and performing functional assays is desirable.

The successful candidate will be expected to provide training in lab techniques to students within the group and help with the overall management of the lab.

 
This is a full time post (35 Hours per week), and you will be offered a fixed term contract until 27/04/2026.