Snabbfakta
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- Paris
Ansök senast: 2024-06-23
Research Associate
We are is using a novel glycan engineering approach to deliver better therapeutics to
those most in need. We engineer drugs by controlling the addition of glycans – essential
sugar molecules found on the surface of drugs – to enhance drug specificity, activity, and
longevity. We have developed a proprietary technology to control the glycans added to
drugs and have a patent pending.
We are a dynamic, international, early-stage startup backed by Entrepreneur First, the
world’s leading talent investor, along with European and US investors. We have
established collaborations with KOLs across the globe and is advised by leading professors in
the field and a former Sanofi VP. We have recently won numerous prestigious research
grants including the iLab Concours d'Innovation (BPI France), the Women TechEU (European
Innovation Commission), and Innov'up Leader PIA (BPI France).
Tasks
You will work directly with the Senior Scientist in a dynamic role taking on various projects
and tasks. The role involves a mixture of research and bench work. Your main functions will
include:
• Producing and analyzing recombinant therapeutic proteins from our CHO cell panel
• Optimizing protein expression in our CHO cell lines, coordinating with third parties
where required
• Quality reporting of cell banks
• Identifying collaborators and KOLs from scientific articles, conferences, and
networking, and leading discussions with them
• Establishing and managing collaborations with academic groups
6 rue Jean Calvin – 75005 Paris – France
• Analyzing competitive landscapes, including patent literature
• Contributing to set up and development of in-house analytical studies
• Providing insights and recommendations for strategic decision making
• Supporting in expanding out our laboratory facilities
Requirements
PhD in cell and molecular biology, biochemistry, biological engineering, or other life
science discipline
• Experience in CHO cell line culture and development, which includes:
o Vector design and cloning; Stable and transient transfections; Single cell clone
selection (FACS or serial dilutions); Research Cell Banking (RCB) generation; Cell
line stability assessment studies; Genetic characterization methods (qPCR, whole
genome sequencing)
• Experience in recombinant monoclonal antibody production and purification, which
includes:
o Cell supernatant harvesting and clarifying; Titer measurements (ELISA/Octet);
Antibody purification (affinity and gel filtration chromatography); Protein sample
prep for downstream analysis (buffer exchange, concentrating); in vitro and cell-
based activity assays (antigen binding, ADCC activity, etc.)
• Entrepreneurial mindset:
o As an early-stage start-up, we need someone who can adapt quickly to shifting
priorities, take initiative, and be proactive in contributing to the success of the
team
• Fluency in English
• Excellent command of scientific literature and writing skills
• Ability to multitask and manage multiple projects simultaneously
• Exceptional organizational skills
• Ability to think in a creative manner to solve problems – a strong bias to action
• Able to work in a timely manner to meet tight deadlines
• Quick learner and eager to take on new tasks outside of comfort zone
• Great communication skills and open to both giving and receiving feedback
• A team player who is strongly invested in our mission and is excited to
get involved in all aspects of company building
Benefits
Opportunity to be a member of the founding team of an innovative startup
• Work directly with the Senior Scientist in our dynamic R&D team in the center of
Paris: our labs are based at the IPGG in Paris 5ème, right off Rue Mouffetard!
• Competitive research salary
• Employee first mentality. We will do everything we can for employee mental and
physical health. Down time will be respected. Annual leave will be generous. Breaks
are strongly encouraged. Rest is an essential component of productivity!
• The opportunity to help bring advanced drugs to the market, improving the lives of
millions of people
We are committed to building a diverse and inclusive workplace. We welcome
applications from people from all walks of life.
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