Researcher - Protein Metrology - LGC National Laboratories

Job Description

LGC provides a range of measurement products and services which underpin the safety, health and security of the public, including reference materials and proficiency testing, genomics solutions, services and instrumentation, and expert sample analysis and interpretation. Our customers are across a number of end markets including Government, Academia Pharmaceuticals, Agricultural Biotechnology, Food, Environment.

The Protein Mass Spectrometry team delivers high quality measurement research projects to meet current and future analytical challenges as part of the LGC’s international role as the UK’s National Measurement Laboratory and Designated Institute (DI) for chemical and bio-measurement. 

The job holder will contribute to the development and validation of analytical methods to deliver NML measurement research programmes for government as well as to support private sector R&D contract commitments within the scope of protein analysis. They will be required to use advanced instrumental techniques and to employ a variety of sample preparation techniques as required.

The successful candidate will have experience in protein structural characterisation by mass spectrometry. Training as appropriate will be provided on traceability of measurements to the System of International Units and on the instruments required for the delivery of the projects. This is an excellent opportunity for candidates looking to progress their career in protein mass spectrometry.

Key Responsibilities

• Independent day-to-day planning and delivery of challenging research and development work to quality, time and budget
• Delivery of proteins and peptides metrology projects with main focus on protein structural characterisation
• Publication and dissemination of scientific developments and achievements.
• Provision of support with the formulation of R&D commercial contracts
• Build relationships with external stakeholders/collaborators, develop and extend metrology networks to underpin the UK national measurement system
• Delivery of ad-hoc research commercial projects and reporting results

• PhD or equivalent experience from industry or academic or clinical research
• Extensive knowledge of protein structure and dynamics

• Hand-on experience with HDX-MS, ion mobility mass spectrometry, native MS, CIU and crosslinking for protein structural analysis
• Experience in the use of sample preparation approaches and hyphenated mass spectrometry for protein quantification is desirable
• Troubleshooting and method development
• Familiarity with bioinformatics tools and software for mass spectrometry data analysis
• Proficiency in data analysis and interpretation related to protein mass spectrometry
• Good presentation skills, both oral and written
• Experience of planning long and short-term research projects, working within deadlines and reporting

Person Specification

The role requires an enthusiastic scientist who will contribute to the successful delivery of analytical R&D projects. You will be expected to promote your achievements with appropriate scientific publications, reports and presentations. The following person specifications are required:

• Being able to work on long term and short-term projects
• Enthusiastic and innovative scientist
• Self-reliant and self-motivated team player
• Good inter-personal skills.
• Attention to detail and a positive attitude to learning
• An appreciation of the importance of working within a quality system and knowledge of good laboratory practice

ABOUT LGC:

LGC is a leading, global life science tools company, providing mission-critical components and solutions into high-growth application areas across the human healthcare and applied market segments. Its high-quality product portfolio is comprised of mission-critical tools for genomic analysis and for quality assurance applications, which are typically embedded and recurring within our customers’ products and workflows and are valued for their performance, quality, and range. 

OUR VALUES

• PASSION
• CURIOSITY 
• INTEGRITY
• BRILLIANCE
• RESPECT

EQUAL OPPORTUNITIES 

LGC strongly believes that every job applicant and employee should be valued for their individual talents regardless of age, disability, race, color, ethnic or national origin, sex, sexual orientation, gender reassignment, marital or civil partnership, pregnancy or maternity, religion, or belief. Short listing, interviewing and selection will always be carried out without regard to gender, sexual orientation, marital status, color, race, nationality, ethnic or national origins, religion or belief, age, or trade union membership.

For more information about LGC, please visit our website www.lgcgroup.com

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