Snabbfakta
-
- Cambridge
Ansök senast: 2024-11-15
Structural Bioinformatician
The role will involve the application of structural bioinformatics approaches to all aspects of Astexs drug discovery process. This will include the identification and assessment of potential new targets from a structural perspective and developing new inhouse structural bioinformatics tools. It will involve taking data from public domain structural databases and our extensive inhouse structure collection and integrating this with proteomics genomics and biological data resources.
You will be part of a team that includes bioinformaticians biologists computational chemists and structural biologists. There will be opportunities for research into novel methods including machine learning based approaches.
The ideal candidate should have a sound knowledge of protein structure and function and be familiar with mining diverse datasets e.g. PDB protein sequences structure prediction homology phylogeny and model organism data. You should also have demonstrable programming expertise excellent communication skills and the ability to work in multidisciplinary teams.
Principal Responsibilities:
- Apply structural bioinformatics for target mining and/or analysis
- Support ongoing drug discovery projects e.g. assessment of potential selectivity issues
- Develop tools for mining visualising threedimensional protein structural information integration with multiomics biological data
Preferred skills and Experience:
- Ph.D. in structural bioinformatics structural biology bioinformatics computational biology computer science or related discipline
- Experience analysing protein structures and sequences
- Proficiency in Python
- Good understanding of standard statistical methods and their usage
- Excellent team working written and verbal communication skills
- Experience with machine learning methods would be an advantage but is not a requirement
/jobs/view/46498a56751ca7253ed6fd4dc87904b9
Remote Work :
No
