About your role
As a PhD student, you will focus on:
- developing next-generation retinal organoids;
- generating 3D bioprinted retinal tissues to study RPE–photoreceptor–endothelial interactions under controlled conditions;
- characterizing organoids and bioprinted tissues using molecular, cellular, and functional assays (e.g., immunostaining, gene expression analysis, imaging, electrophysiology, or other functional readouts);
- generating patient-specific iPSC-derived photoreceptors to model disease phenotypes and investigate degeneration mechanisms;
- evaluating regenerative strategies, including photoreceptor cell therapy, gene therapy, and small-molecule interventions, to restore photoreceptor function and assess tissue integration;
- collaborating with interdisciplinary teams, including experts in iPSC technology, retinal biology, and translational regenerative medicine;
- publishing in international peer-reviewed journals and presenting findings at conferences.
About youFor this project, we are seeking a motivated PhD candidate with a strong interest in regenerative medicine, stem cell and organoid technologies, and retinal research. Moreover, you:
- have a completed MSc (or equivalent) in Cell biology, Molecular biology, Biomedical sciences, Neuroscience, Ophthalmic research, or related field;
- preferably have experience with stem cell cultures (iPSCs), 3D culture or organoid systems, bioprinting, molecular and cellular biology assays, imaging, and/or functional characterization;
- have excellent English communication skills;
- work well independently as well as collaboratively in a multidisciplinary team;
- have the ambition to complete a PhD thesis and develop as a researcher.
Candidates with additional experience in translational research, preclinical studies, or cell therapy are strongly encouraged to apply.
Our offer- Access to state-of-the-art facilities for stem cell research, 3D bioprinting, organoid culture, and retinal biology.
- Mentorship from experienced Principal Investigators with expertise in retina, iPSC technology, and translational research.
- Opportunity to shape your own research direction within the theme of next-generation retinal organoids and RPE–photoreceptor–endothelial interactions in 3D tissues.
- A stimulating, collaborative, and inclusive work environment with multidisciplinary expertise.
- You will be employed by Amsterdam UMC Research BV.
- A contract for 12 months, with the intention to extend for a total of 4 years. The Guideline PhD contract applies to this vacancy.
- Salary scale OIO: € 3.108 to € 3.939 gross based on full-time employment (depending on education and experience) and a year-end bonus of 8.3%. Calculate your net salary here.
- Holiday hours: 190.4 per year for fulltime and a possibility to save additional hours.
- Pension accrual with BeFrank, a modern, comprehensible and fairly priced pension.
- For >7 km each way, 100% reimbursement for public transport travel costs and, for private transport, €0.18 per km up to a maximum of 40 km each way.
- Do you prefer walking or cycling? Take advantage of our good bike scheme. Moreover, you will receive a reimbursement of €0.18 per km.
Watch this video with more information about joining Amsterdam UMC Research BV.
