Snabbfakta
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- Cambridge
Ansök senast: 2024-11-26
Research Assistant in Cell Biology (Fixed Term)
Applications are invited for an enthusiastic and committed graduate research assistant to join a vibrant team investigating the cell biology of a group of neurological conditions called hereditary spastic paraplegias. This project is based in the group of Professor Evan Reid at Cambridge Institute for Medical Research and is funded for 1 year. It would suit a recent biological sciences graduate who would like to obtain more practical laboratory experience before embarking on a PhD.
The project aims to understand the functions of hereditary spastic paraplegia proteins in the molecular pathogenesis of axonal degeneration. The work will be at the interface between cell biology (especially membrane traffic) and molecular neuroscience, and will focus on functional genomic synthetic lethality screens using iPSC-derived neuronal models of HSP. The lab employs an integrated approach that combines state of the art cell biology, biochemistry, proteomics, functional genomics and stem cell-derived neuronal modeling. We aim to produce high quality research that impacts our field and stands the test of time. Cambridge Institute for Medical Research is a centre of excellence that has a strong focus on understanding the molecular mechanisms of disease, with the aim of translating basic discoveries to clinically meaningful therapies. It is known for its positive research culture.
Candidates must have experience in molecular cell biology or molecular neuroscience, and must by the time of appointment have a BSc in the biological, biochemical or biomedical sciences. Previous research experience would be highly desirable, especially if in one of the following areas; CRISPR-Cas genome editing, stem cell culture and neuronal differentiation, fixed or live cell immunofluorescence microscopy (especially super-resolution), lentiviral delivery of RNA or DNA to cultured cells.
Applicants will work under the practical supervision of a post-doctoral researcher to achieve the aims of this project. They will be expected to work within a highly interactive group, to have a friendly and collegiate outlook, to have good written and verbal communications skills, to be well-organised and have the ability to work calmly to meet deadlines.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
