Postdoctoral - Cardiac Regeneration (Microscopy) (M/ F)

Institut Curie is a major player in the research and fight against cancer. It consists of a Hospital group and a Research Center of more than 1000 employees with a strong international objective of the Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

We are looking for a highly motivated and productive post-doctoral fellow to join our team “Mechanisms of Cardiac Regeneration” headed by Phong NGUYEN (), at Institut Curie, Paris, France. Our research interests focus on uncovering the factors and mechanisms that allow the zebrafish heart to naturally recover and regenerate from an injury.

The project

Our lab has recently developed an optimized method to maintain and image injured cardiac tissue from the adult zebrafish over an extended time period. As a result, we are now able to visualize and track live cell behaviours and their interactions, with their environment in a 3D context. These observations are further tested genetically with the use of gain- and loss-of-function methods. By focusing on specific aspects of regeneration, this project will uncover novel mechanisms on how the zebrafish can naturally and successfully regenerate its heart. This project will be supported by FRM (Foundation pour la Recherche Médicale) and Labex DEEP.

Training and Skills required:

We are looking for a postdoc in cardiac regeneration (Microscopy) candidate:

- The candidate should hold a PhD in biology, cell biology, genetics or related areas.

- Fresh PhD graduates or with up to 3 years of postdoctoral experience. Applicants are invited to indicate the specific level of experience in these subjects.

o Expertise preparing and conducting live imaging using microscopes such as laser scanning confocal, spinning disk confocal, Airy scan, multiphoton or lattice light sheet

o Proficient in image analysis such as Imaris or ImageJ

o Proficient in molecular biology skills such as cloning and PCR

o Desirable but not necessary: experience in working with animals or zebrafish handling

o Desirable but not necessary: experience in generating custom scripts for image processing

- Language skills: Fluency in English. French is a plus.

Abilities

- Ability to work independently, organize and manage tasks and be willing to working in a team.

- Ability to effectively communicate in the form of writing, oral presentations, supervising students

- The candidate should be highly motivated, curious, and enthusiastic to work in a collaborative team.

All our opportunities are open to people with disabilities

Contract information

Type of contract : Fixed-term contract (COD)

Starting date: As soon as possible

Duration : 18 months (renewable contract up to 3 years)

Working time : full time

Remuneration : according to the current grids

Benefits : Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance

Location of the position : Paris, 5eme

Reference: NA

Please send your CV, letter of motivation and 3 references

CVs to be processed on the go, therefore the position could be filled before the deadline for applications.

Publication date: 17/06/2024

Deadline for application: 31/08/2024

Institut Curie is an inclusive, equal opportunity employer

and is dedicated to the highest standards of research integrity.