Snabbfakta
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- Norwich
Ansök senast: 2024-10-12
Postdoctoral Researcher (Morgan Group)
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Morgan Group at the John Innes Centre, working on cutting-edge science in the field of Cell & Developmental Biology.
About the John Innes Centre
The John Innes Centre is an independent, international centre of excellence in plant and microbial sciences. We nurture a creative, curiosity-led approach to answering fundamental questions in bioscience, and translate that knowledge into societal benefits. Our strategic vision, , sets out our ambitious long-term goals for the game changing impact of our science globally.
Our employees enjoy access to state-of-the-art technology and a diverse range of specialist training opportunities, including support for leadership and management. Click here to find out more about working at the John Innes Centre.
About the Morgan Group
Research in the Morgan group focuses on understanding the mechanism of meiotic recombination, including the enigmatic phenomena of crossover interference. We combine advanced super-resolution imaging with genetics, genomics and biochemistry to investigate meiotic recombination, using Arabidopsis and wheat as model eukaryotes. Additionally, we regularly collaborate with groups specialising in other disciplines (e.g. mathematical modellers) to more comprehensively answer complex biological questions. See, for example, Morgan et al. 2021, Nat Comms 12, 4674.
The role
The successful applicant will study the biochemistry of meiotic recombination proteins in Arabidopsis. Determining the activity, putative targets and oligomerisation properties of the recombination machinery in Arabidopsis will be vital for addressing key, open questions relating to meiotic crossover formation, such as what are the underlying biophysics behind recombination protein coarsening dynamics and how might this drive crossover designation?
The ideal candidate
The successful applicant will use a combination of advanced microscopy, molecular biology and genetics to study the mechanism of meiotic recombination in Arabidopsis.
Investigating the spatiotemporal localisation and dynamic behaviour of the recombination machinery in Arabidopsis will be vital for understanding the mechanisms that govern the frequency and positioning of meiotic crossovers. The Postdoctoral Researcher will be responsible for addressing these questions using a combination of live-imaging, super-resolution microscopy, molecular biology and genetic dissection.
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