Academic World News

Tuberculosis vaccine passes safety test

No other infectious disease has killed more people than tuberculosis. Currently, only one vaccine is available to prevent severe courses: Bacillus Calmette Guérin (BCG). However, it is not equally effective against all types of tuberculosis. Especially infants and immunocompromised patients are therefore in urgent need for more effective tuberculosis vaccines. A clinical trial in South Africa has now shown that the new vaccine candidate VPM1002, developed by Max Planck researcher Stefan H.E. Kaufmann and his team, is equally safe for newborns with and without HIV exposure and has fewer side effects compared to BCG.

Similarity between schizophrenia and dementia

Researchers for the first time compared schizophrenia and frontotemporal dementia, disorders that are both located in the frontal and temporal lobe regions of the brain. The idea can be traced back to Emil Kraepelin, who coined the term "dementia praecox" in 1899 to describe the progressive mental and emotional decline of young patients. His approach was quickly challenged, as only about 25 percent of those affected showed this form of disease progression.

Study achieves longest continuous tracking of migrating insects

Insects are the world’s smallest flying migrants, but they can maintain perfectly straight flight paths even in unfavorable wind conditions, according to a new study from the Max Planck Institute of Animal Behavior and the University of Konstanz. Researchers radio tracked migrating hawkmoths for up to 80 kilometers—the longest distance that any insect has been continuously monitored in the wild. By closely following individuals during migration, the world-first study unlocks a century-old mystery of what insects do over their long-range journeys.

Sweet sap, savory ants

Many mammals have a sweet tooth, but birds lost their sweet receptor during evolution. Although hummingbirds and songbirds independently repurposed their savory receptor to sense sugars, how other birds taste sweet is unclear. Now, an international team lead by researchers from the Max Planck Institute for Biological Intelligence (in foundation) shows that woodpeckers also regained sweet taste. Interestingly, wrynecks, specialized ant-eating woodpeckers, selectively reversed this gain through a simple and unexpected change in the receptor. These results demonstrate a novel mechanism of sensory reversion and highlight how sensory systems adapt to the dietary needs of different species.

Vital ventilation

Dying reefs and once-vibrant corals that have since lost all colour: climate change is having massive effects on the architects of undersea cities. As waters grow warmer, the phenomenon of “coral bleaching” continues to spread. Yet not all corals are equally susceptible. An international team led by Cesar Pacherres and Moritz Holtappels from the Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research (AWI) in Bremerhaven and Soeren Ahmerkamp from the Max Planck Institute for Marine Microbiology in Bremen may have found the explanation: using minuscule filaments (cilia), corals can influence the currents in their immediate vicinity, protecting themselves from harmful oxygen concentrations, as the experts report in the journal Current Biology.

Origins of the Black Death identified

The Black Death, the biggest pandemic of our history, was caused by the bacterium Yersinia pestis and lasted in Europe between the years 1346 and 1353. Despite the pandemic’s immense demographic and societal impacts, its origins have long been elusive. Now, a multidisciplinary team of scientists, including researchers from the Max Planck Institute for Evolutionary Anthropology in Leipzig, the University of Tübingen, in Germany, and the University of Stirling, in the United Kingdom, have obtained and studied ancient Y. pestis genomes that trace the pandemic’s origins to Central Asia.

Shedding light on linguistic diversity and its evolution

Scholars from the Max Planck Institute for Evolutionary Anthropology in Germany and the University of Auckland in New Zealand have created a new global repository of linguistic data. The project is designed to facilitate new insights into the evolution of words and sounds of the languages spoken across the world today. The Lexibank database contains standardized lexical data for more than 2000 languages. It is the most extensive publicly available collection compiled so far.

Britains earliest humans

Archaeological discoveries made on the outskirts of Canterbury, Kent (England) confirm the presence of early humans in southern Britain between 560,000 and 620,000 years ago. The breakthrough, involving controlled excavations and radiometric dating, comes a century after stone tool artefacts were first uncovered at the site. The research, led by archaeologists at the University of Cambridge, confirms that Homo heidelbergensis, an ancestor of Neanderthals, occupied southern Britain in this period – when it was still attached to Europe – and gives tantalizing evidence hinting at some of the earliest animal hide processing in European prehistory.

Tobacco hawkmoths always find the right odor

A research team at the Max Planck Institute for Chemical Ecology has discovered how tobacco hawkmoths are able to detect odors that are important to them against a complex olfactory background. By looking at the specific activity patterns that the odors triggered in the moths' brains the researcher showed that the sense of smell enables moths not only to perceive the intense floral odors of nectar sources, but also to find the rather unobtrusive smell of their host plants on which the larvae thrive. What is especially amazing is that tobacco hawkmoths can reliably detect the odors of their host plants despite the multitude of background odors emitted by many other plants in the vicinity.

Great white sharks may have contributed to megalodon extinction

The diet of fossil extinct animals can hold clues to their lifestyle, behaviour, evolution and ultimately extinction. However, studying an animal’s diet after millions of years is difficult due to the poor preservation of chemical dietary indicators in organic material on these timescales. An international team of scientists led by the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, applied a new method to investigate the diet of the largest shark to have ever existed, the iconic Otodus megalodon. This new method investigates the zinc isotope composition of the highly mineralised part of teeth and proves to be particularly helpful to decipher the diet of these extinct animals.

Misperceptions about doctors’ trust in Covid-19 vaccines influence vaccination rate

How to increase vaccination rates by autumn, without any compulsion is shown by an international research team including the Max Planck Institute for Tax Law and Public Finance. They found that people’s willingness to get vaccinated is related to the presumed trust the medical doctors have in the vaccines. However, the study shows a large discrepancy between the assumptions of the population and the actual views of the medical profession.

A Center for Visual Computing and Artificial Intelligence

The Max Planck Institute for Informatics in Saarbrücken (Germany) and Google have agreed on a strategic partnership to establish the Saarbrücken Research Center for Visual Computing, Interaction and Artificial Intelligence (VIA) at the MPI for Informatics. The center will conduct basic research in frontier areas of computer graphics, computer vision, and human machine interaction, at the intersection of artificial intelligence and machine learning. The VIA center will be headed by Christian Theobalt, scientific director at the Max Planck Institute for Informatics.